Nintoin Suspension | 100ml | ePharma
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Nintoin Suspension 100ml

Generic: Nitrofurantoin

Type: Suspension

Pack Size: 100ml

Nintoin Suspension (Nitrofurantoin 25/5mg/ml) is a bactericidal antibiotic that helps to treat or prevent urinary tract infections. It should be used with caution in patients with kidney disease. 


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Discount Price: ৳ 75.2
MRP: ৳ 80 6% Off

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✅ Description:

  • Nintoin Suspension is an antibiotic medication that is used to treat and prevent urinary tract infections. These infections can affect various parts of the urinary system, including the bladder, kidneys, ureters, and urethra. Symptoms of urinary tract infections include a strong and constant urge to urinate, a burning sensation during urination, reduced urine flow, cloudy urine, blood in urine, and pelvic pain, especially in women.
  • Your doctor will regularly monitor the functioning of your lungs and liver while you are taking Nintoin Suspension. It may also interfere with urine tests for sugar, leading to false positive results.
  • Caution should be exercised when taking Nintoin Suspension in patients with lung or liver disease, anemia, diabetes (high blood sugar), conditions causing severe weakness, electrolyte imbalances, and vitamin B deficiency, and recommended for use in patients with severe kidney disease.
  • Pregnant women are not recommended to use Nintoin Suspension during labor or delivery due to potential harm to the baby. Breastfeeding women should use it with caution.
  • This medicine should not be used in infants below 3 months of age. Elderly patients should use Nintoin Suspension with caution.
  • The most common side effects of Nintoin Suspension include nausea, vomiting, loss of appetite, and diarrhea. If any of these side effects worsen, it is advisable to consult your doctor.

Safety Advices


Alcohol
UNSAFE

Avoid consumption of alcohol while taking Nintoin Suspension because it might make you dizzier.  


Pregnancy
CONSULT YOUR DOCTOR

Nintoin Suspension can be used during pregnancy only if prescribed by your doctor. It should, however, not be used at this stage of pregnancy (during labor or delivery) as it may harm the unborn baby. It is essential to always consult a doctor before starting any medicine during pregnancy.


Breastfeeding
CONSULT YOUR DOCTOR

As Nintoin Suspension is known to pass into breast milk, you should consult your doctor before using this medicine during breastfeeding.


Driving
CAUTION

Nintoin Suspension may cause dizziness and drowsiness, hence you need to be cautious while driving.


Kidney
CONSULT YOUR DOCTOR

Nintoin Suspension is not recommended for use in patients with kidney disease that severely affects the function of the kidneys. It should be used with caution in patients with kidney problems. Consult your doctor before taking Nintoin Suspension


Liver
CONSULT YOUR DOCTOR

Nintoin Suspension should be taken with caution in patients with liver disease. Consult your doctor before taking Nintoin Suspension 

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✔️ Uses of Nintoin Suspension
  • Treatment of Bacterial infections of the urinary tract
✔️ How does Nintoin Suspension work?

Nintoin Suspension effectively treats and prevents urinary tract infections by killing bacteria present in the urethra, bladder, and/or kidneys. It mainly acts by disrupting the production of genetic material present in the bacterial cell.

✔️ Side Effects of Nintoin Suspension
  • Skin rash
  • Fever and chills
  • Burning or tingling sensation
  • Headache
  • Drowsiness
  • Diarrhea
  • Excessive gas in the stomach
✔️ Quick Suggestions:
  • Nintoin Suspension treats and prevents uncomplicated urinary tract infections.
  • Finish the prescribed course of medicine, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Take it with food to avoid nausea, which is a common side effect.
  • It can turn your urine a dark yellow or brown color. This is normal and nothing to worry about.
  • Do not take it for longer or more often than prescribed by your doctor.
✔️ Indication of Nintoin Suspension

Nintoin Suspension is an antibiotic medicine. It is used for the treatment and prevention of uncomplicated urinary tract infections.

✔️ Pharmacology

Nitrofurantoin is an antibacterial agent that works particularly well for infections of the urinary tract. Extremely solvent in urination, nitrofurantoin may give poop a brown hue. Ribosomal proteins and other macromolecules produced by bacteria are inactivated or altered by nitrofurantoin. It has been demonstrated that nitrofurantoin is effective against pursuing microscopic organisms: Grass-Feeding Aerobes Enterococcus faecalis, Staphylococcus aureus, Streptococcus agalactiae, Gather D streptococci, and Viridans gather streptococci are among the staphylococci that are Coagulase-negative and include Staphylococcus epidermidis. Escherichia coli, Citrobacter amalonaticus, Citrobacter diversus, Citrobacter freundii, Klebsiella oxytoca, and Klebsiella ozaena are examples of Gram-negative Aerobes.

✔️ Dosage & Administration of Nintoin Suspension

The recommended dosage of Nitrofurantoin suspension for children is 5-7 mg/kg/day, divided into four doses per day. However, it is contraindicated for use in infants under one month of age. The average doses for pediatric patients are as follows:

  • For children weighing 7 to 11 kg: Administer ½ (2.5 ml) teaspoonfuls four times daily.
  • For children weighing 12 to 21 kg: Administer 1 (5 ml) teaspoonful four times daily.
  • For children weighing 22 to 30 kg: Administer 1½ (7.5 ml) teaspoonfuls four times daily.
  • For children weighing 31 to 41 kg: Administer 2 (10 ml) teaspoonfuls four times daily.

Treatment should be continued for one week or at least 3 days after the urine becomes sterile. In some cases, for long-term suppressive therapy in children, lower doses of 1 mg/kg per 24 hours may be sufficient. This dose can be given as a single dose or divided into two doses.

Always take Bevon Suspension as advised by the physician. Shake well before use. Do not exceed the recommended daily dosage. Use a measuring cup or a spoon to properly measure the dose. Do not take Bevon Suspension if you are allergic to any of its components.

✔️ Interaction

When Nitrofurantoin is taken together with antacids containing Magnesium Trisilicate, it can interfere with the absorption and effectiveness of certain uricosuric medicines, such as Probenecid and Sulfinpyrazone. Uricosuric medicines are used to treat conditions like gout by increasing the excretion of uric acid from the body.

The presence of Magnesium Trisilicate in antacids can reduce the absorption rate and extent of these uricosuric medicines, making them less effective in lowering uric acid levels. Additionally, Nitrofurantoin can also be affected by the interaction with Magnesium Trisilicate, as it can limit the secretion of Nitrofurantoin in the renal tubules (part of the kidney involved in urine formation and excretion).

To ensure the optimal effectiveness of both Nitrofurantoin and uricosuric medicines, it is advisable to separate their administration. It is recommended to take Nitrofurantoin and uricosuric medicines at different times, with an appropriate time interval between them. This helps to avoid any potential interactions and allows for proper absorption and effectiveness of each medication.

✔️ Contraindications
  • Severe Renal Impairment: If you have severe renal impairment, such as anuria (absence of urine production), oliguria (reduced urine production), significantly elevated serum creatinine levels, or creatinine clearance (CrCl) below 60 ml/min, the use of nitrofurantoin may be contraindicated or require dosage adjustment. Your healthcare provider will determine the appropriate course of action.
  • Hypersensitivity to Nitrofurans: If you have a known hypersensitivity or allergic reaction to nitrofurans or any components of nitrofurantoin, its use should be avoided. Allergic reactions can range from mild skin rashes to severe systemic reactions, including anaphylaxis.
  • G6PD Deficiency: Nitrofurantoin use should be avoided in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. G6PD deficiency is an enzyme deficiency that can lead to hemolysis (destruction of red blood cells) when exposed to certain medications, including nitrofurantoin.
  • Infants Under 3 Months of Age: Nitrofurantoin is not recommended for use in infants younger than 3 months old. Safety and efficacy data in this age group are limited.
  • Pregnancy at Term, During Labor and Delivery, or Imminent Onset of Labor: Nitrofurantoin should not be used in pregnant women at term (near the end of pregnancy), during labor and delivery, or when the onset of labor is imminent. There is a potential risk to the baby during these stages.
✔️ Pregnancy & Lactation

Pregnancy Category B. Limited and inconclusive studies have been conducted on the use of this medication in pregnant women. It should only be used during pregnancy if it is absolutely necessary. Small amounts of nitrofurantoin have been detected in human breast milk. Considering the potential for significant side effects in nursing infants under one month old, a decision should be made regarding whether to discontinue breastfeeding or discontinue the medication, taking into account the importance of the drug to the mother.

✔️ Precautions & Warnings

In elderly patients, caution should be exercised when using Nitrofurantoin. It is important to monitor hepatic (related to the liver) and pulmonary (related to the lungs) function during prolonged therapy to ensure the medication is well-tolerated and does not cause any adverse effects.

If a patient has pre-existing pulmonary, hepatic, neurological, or allergic disorders or a predisposition to peripheral neuropathy (damage to the nerves in the extremities), special care should be taken when considering the use of Nitrofurantoin. This includes individuals with conditions such as renal impairment (kidney dysfunction), anemia, diabetes mellitus (high blood sugar), electrolyte imbalance, debility (weakness), and vitamin B deficiency.

If signs of peripheral neuropathy, such as numbness, tingling, or pain in the hands or feet, occur during treatment with Nitrofurantoin, the medication should be discontinued.

Regarding lactation, Nitrofurantoin enters breast milk. Therefore, it is recommended to discontinue the drug or avoid nursing while taking Nitrofurantoin to prevent potentially adverse effects on the breastfed infant.

✔️ Storage Conditions

Do not store above 30°C. Keep away from light and out of the reach of children.

Frequently Asked Questions (FAQ)

You can take Nintoin Suspension for as long as a doctor has prescribed you. It's important that you keep taking Nintoin Suspension until your course is finished. You should not stop the treatment in between even if you see improvement in symptoms. It will help stop the infection from coming back.

Yes, Nintoin Suspension is generally used in children (under 6 years) and infants above 3 months of age. It is not recommended for infants below three months. Your child’s doctor will decide the correct dose or select a suitable alternative therapy for your child.

No, Nintoin Suspension belongs to a class of medication called antibiotics, which works by killing bacteria. This medicine is mainly used in the treatment of urinary tract infections. It does not work for cold, flu and other viral infections.

You should always take Nintoin Suspensionalong with food or milk. Taking this medicine along with food or milk makes it work more effectively against urinary tract infections. This will also prevent stomach upset and help the absorption.

Nausea, vomiting, diarrhoea, loss of appetite, headache, dizziness are a few common side effects of Nintoin Suspension. However, these symptoms are usually mild and resolve on your own. Also, it is not important that everyone experience the same.
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Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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